In the metastatic setting, oncologists can now choose between diverse monotherapy or a combination of gemcitabine, fluorouracil, nabpaclitaxel, oxaliplatin, irinotecan, and liposomal irinotecan. Colorectal cancer is currently the third deadliest cancer in the united states and will claim an estimated 49,190 u. Clinical colorectal cancer is devoted to articles on detection, diagnosis, prevention, and treatment of colorectal, pancreatic, liver, and other gastrointestinal cancers. Colorectal cancer crc is today the most frequent type of cancer, with a higher incidence in men. Recent clinical colorectal cancer articles elsevier. Cancers of the colon represent the third leading cause of neoplasiarelated morbidity and mortality in the united states and canada committee ccss 2009. The panel believes that a multidisciplinary approach is necessary for managing colorectal cancer. Current options for thirdline and beyond treatment of metastatic colorectal cancer. Venook, lynette cederquist, emily chan, yi jen chen, harry s.
Epidemiology of colorectal cancer pubmed central pmc. Besides an ageing population and dietary habits of highincome countries, unfavourable risk factors such as obesity, lack of physical exercise, and smoking increase the risk of colorectal cancer. The impact of physical activity on cancer recurrence and survival in patients with stage iii colon cancer. Colorectal cancers contain numerous quantitative and qualitative differences in metabolic and synthetic enzyme activities compared with normal colonic mucosa, which may. The recommended surgical procedure for resectable colon cancer is an en bloc resection and adequate lymphadenectomy. Several glycoprotein markers for colon cancer have been studied whose diagnostic accuracy may surpass the limited sensitivity and specificity of traditional markers such as cea.
Recent clinical colorectal cancer articles recently published articles from clinical colorectal cancer. Estadonutricionaldepacientesconneoplasiasdeltracto. The journal is devoted to articles on detection, diagnosis, prevention, and treatment of colorectal, pancreatic, liver, and other gastrointestinal cancers. Find out more about publishing open access with us here. International agency for research on cancer iarc, oms, 2012. The lifetime risk for colon cancer is estimated to be 1 in 20 persons, with a median age of diagnosis of 71 years jemal et al. Nowadays, it is the worlds fourth most deadly cancer with almost 900 000 deaths annually. With clinical colorectal cancer indexed in cinahl, chemical abstracts, ebscohost, embase, journal citation reports, ovid, pubmedmedline, pubmedmedline and scopus. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Clinical colorectal cancer is devoted to articles on detection, diagnosis, prevention, and treatment of. However, it has become a predominant cancer and now accounts for approximately 10% of cancerrelated mortality in western countries.
Colorectal cancer welcomes unsolicited article proposals. Early colonoscopy improves the outcome of patients with symptomatic colorectal cancer. Clinical colorectal cancer is a part of elsevier s oncology journal network. Dietary fibre, whole grains, and risk of colorectal cancer. Atencion primaria y deteccion del cancer colorrectal elsevier. Colorectal cancer had a low incidence several decades ago. However, it has become a predominant cancer and now accounts for approximately 10% of cancer related mortality in western countries. In terms of incidence, colorectal cancer is the fourth in frequency in men. Email us today to discuss the suitability of your research and our options for authors, including accelerated publication. This means there are more chemotherapy drugs available for pancreatic cancer than for colon cancer. Increased platelet counts were revealed as a predictor of cancer in patients with an occult malignancy bailey et al. Citescore values are based on citation counts in a given year e. The panel endorses the concept that treating patients in a clinical trial has priority over standard or accepted therapy.
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